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ECG-MoE: Mixture-of-Expert Electrocardiogram Foundation Model

arXiv:2603.04589v1 Announce Type: new Abstract: Electrocardiography (ECG) analysis is crucial for cardiac diagnosis, yet existing foundation models often fail to capture the periodicity and diverse features required for varied clinical tasks. We propose ECG-MoE, a hybrid architecture that integrates multi-model temporal features with a cardiac period-aware expert module. Our approach uses a dual-path Mixture-of-Experts to separately model beat-level morphology and rhythm, combined with a hierarchical fusion network using LoRA for efficient inference. Evaluated on five public clinical tasks, ECG-MoE achieves state-of-the-art performance with 40% faster inference than multi-task baselines.

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Yuhao Xu, Xiaoda Wang, Yi Wu, Wei Jin, Xiao Hu, Carl Yang
· · 1 min read · 3 views

arXiv:2603.04589v1 Announce Type: new Abstract: Electrocardiography (ECG) analysis is crucial for cardiac diagnosis, yet existing foundation models often fail to capture the periodicity and diverse features required for varied clinical tasks. We propose ECG-MoE, a hybrid architecture that integrates multi-model temporal features with a cardiac period-aware expert module. Our approach uses a dual-path Mixture-of-Experts to separately model beat-level morphology and rhythm, combined with a hierarchical fusion network using LoRA for efficient inference. Evaluated on five public clinical tasks, ECG-MoE achieves state-of-the-art performance with 40% faster inference than multi-task baselines.

Executive Summary

This article proposes ECG-MoE, a hybrid architecture for electrocardiogram (ECG) analysis, integrating multi-model temporal features with a cardiac period-aware expert module. ECG-MoE achieves state-of-the-art performance on five public clinical tasks, significantly outperforming multi-task baselines and reducing inference time by 40%. The approach leverages a dual-path Mixture-of-Experts to model beat-level morphology and rhythm, combined with a hierarchical fusion network using LoRA for efficient inference. This innovation holds promise for advancing cardiac diagnosis and improving patient outcomes.

Key Points

  • ECG-MoE combines multi-model temporal features with a cardiac period-aware expert module for comprehensive ECG analysis.
  • The proposed architecture achieves state-of-the-art performance on five public clinical tasks, outperforming multi-task baselines.
  • ECG-MoE reduces inference time by 40% through the use of a hierarchical fusion network with LoRA.

Merits

Strength in Clinical Applications

ECG-MoE's ability to achieve state-of-the-art performance on various clinical tasks demonstrates its potential for real-world applications in cardiac diagnosis and patient care.

Efficient Inference

The proposed architecture's 40% reduction in inference time makes it a more practical solution for clinical settings where time is of the essence.

Demerits

Limited Generalizability

The article's focus on five public clinical tasks limits the generalizability of ECG-MoE to broader clinical scenarios and patient populations.

Dependence on Data Quality

The effectiveness of ECG-MoE relies heavily on the quality and diversity of the training data, which may not always be available or representative of real-world clinical settings.

Expert Commentary

The article's innovative approach to ECG analysis and diagnosis demonstrates the potential of deep learning techniques to transform clinical decision-making. However, the limitations of the proposed architecture and the need for further research in data quality and generalizability must be acknowledged. As the field continues to evolve, it is essential to prioritize collaboration between researchers, clinicians, and policymakers to address the complex challenges in cardiac disease diagnosis and treatment.

Recommendations

  • Recommendation 1: Further investigation into the generalizability of ECG-MoE to other medical imaging modalities and clinical tasks is necessary to fully realize its potential.
  • Recommendation 2: The development of standardized data sets and quality control measures is critical to ensure the reliable application of ECG-MoE in clinical settings.

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